Study of the preventive effect of probiotics on postoperative infection after colorectal surgery

Study of the preventive effect of probiotics on postoperative infection after colorectal surgery - Kyorin Probiotics Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004372

Enrollment

Registered

2010-11-01

Start date

2011-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for rectal surgery and stoma closure

Interventions

the grop takes lactic acid bacteria beverage for pre-operative 7 days and post-operative 7 days control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients of 20-80 years old, scheduled for rectal surgery and stoma closure. 2) Patients who agree this clinical trial by themselves.

Exclusion criteria

Exclusion criteria: Patients who had past history of colitis (ulcerative colitis: UC, Crohn's disease,MRSA colitis, pathogenic E. Coli colitis, pseudomembranous enterocolitis)

Design outcomes

Primary

Measure	Time frame
Incidence of SSI	—

Secondary

Measure	Time frame
Changes of stool (bacteria, pH, organic acid) at pre-medication, pre-operation, and 5POD Blood test (WBC, CRP, IL-6, NK activity) at pre-medication, pre-operation, 2POD, and 7POD	—

Countries

Japan

Contacts

Public ContactTakaaki Kobayashi

Kyourin university hospital Department of surgery

ck9t-kbys@asahi-net.or.jp0422-47-5511

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026