Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound

Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound - Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004320

Enrollment

Registered

2010-10-04

Start date

2010-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension, Coronary artery disease

Interventions

Intensive blood pressure control (SBP&lt

120mmHg) Standard blood pressure control (SBP&lt

140mmHg)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who are planning to take CAG or PCI. 2)Patients with primary hypertention: SBP140-180mmHg within one month. 3)20<=Age<80

Exclusion criteria

Exclusion criteria: 1)Patients with severe hypertention. 2)Patients with secondary hypertension. 3)Patients treated hypertention with more than 3 drugs. 4)Patients with coronary artery disease in left main trank. 5)Patients with moderate heart failure. 6)Patients with severe valvelar disease. 7)Patients with liver dysfunction. 8)Patients with renal dysfuction(Cr>=2.0 mg/dL). 9)Pregnant or nursing woman. 10)Patients with uncontrollable arrythmia.

Design outcomes

Primary

Measure	Time frame
The change of percent atheroma volume evaluated by intravascular ultrasound after 18 months.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026