Effects of renin-angiotensin system inhibitors for endothelial function and neointimal coverage after drug-eluting stent implantation. ~Comparative study between angiotensin coverting enzyme inhibitors and angiotensin receptor blockers~

Effects of renin-angiotensin system inhibitors for endothelial function and neointimal coverage after drug-eluting stent implantation. ~Comparative study between angiotensin coverting enzyme inhibitors and angiotensin receptor blockers~ - Effects of renin-angiotensin system inhibitors for endothelial function and neointimal coverage after drug-eluting stent implantation. ~Comparative study between angiotensin coverting enzyme inhibitors and angiotensin receptor blockers~

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004293

Enrollment

Registered

2010-09-29

Start date

2009-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease Hypertension

Interventions

Imidapril 10mg once daily for 8~10 months Termisartan 40mg once daily for 8~10 months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Stable coronary artery disease Patients treated with drug-eluting stent for the first time Hypertension

Exclusion criteria

Exclusion criteria: Acute myocardial infarction Clinical or angiographic coronary vasospasm Symptomatic congestive heart failure Atrial fibrillation Severe valvular heart disease Previous coronary bypass graft surgery Left main coronary artery lesion Bifurcation lesion In-stent restenosis lesion Angiographic in-stent restenosis in follow-up angiography Patients who showed progression of lesions or development of non target lesions or vessels on follow-up angiography

Design outcomes

Primary

Measure	Time frame
Coronary endothelial function and neointimal coverage 8~10 months after stent implantation	—

Countries

Japan

Contacts

Public ContactYoshiaki Mitsutake

Kurume University School of Medicine Department of Internal Medicine, Division of Cardio-vascular Medicine

mitsuhiba@grace.ocn.ne.jp0942-35-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026