fetal tachycarrhythmia(supraventricular tachycadia, atrial flutter)
Conditions
Interventions
These antiarrhythmic agency are administered to pregnant women as treatment for fetal supraventricular tachycardia with short VA interval (start with 2nd for fetal hydrops) 1st. digoxin 2nd. d
Sponsors
National cerebral and cardiovascular center of Japan
National cerebral and cardiovascular center of Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. sustained fetal tachycaarrhythmias with these diagnoses 1) supraventricular tachycardia with short VA interval 2) supraventricular tachycardia with short VA interval 3) atrial flutter 2.22w0d~36w6d 3.singleton 4.IC
Exclusion criteria
Exclusion criteria: 1. impossible to obtain IC due to the mental problem 2. risk for maternal health (ex; allergic to anti-arrhythmic agency) 3. Dr's judgement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sinus rhythm or fetal heart rate <180bpm (the half of 30 min fetal echocardiogram and/ or 40 min CTG ) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. IUFD 2. rate of preterm birth 3. rate of cesarean section 4. fetal heart rate, hydrops 5. neonatal arrhythmias 6. CNS findings in neonate 7. survival rate at 1 month 8. tachyarrhythmias at 1 month (9.MRI at 1month(corrected)) (10.development at 1y 6m(corrected)) (11.development at 3y(corrected)) | — |
Countries
Japan
Contacts
Public ContactTakekazu Miyoshi
National Cerebral and Cardiovascular Center Department of Perinatology and Gynecology
Outcome results
None listed