Perioperative infusion of dexmedetomidine at a high dose reduced postoperative analgesic requirements

Perioperative infusion of dexmedetomidine at a high dose reduced postoperative analgesic requirements - Analgesic effects of dexmedetomidine on postoperative pain status

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004168

Enrollment

Registered

2010-09-07

Start date

2008-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient undergoing radical surgery for malignant gynecological disease

Interventions

Dexmedetomidine is administered at 1mcg/kg/hr in 16 patients undergoing open abdominal surgery for malignant gynecological diseases and postoperative pain status is evaluated. Volume-matched normal s

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients with indication of radical surgery for malignant gynecological disease.

Exclusion criteria

Exclusion criteria: Patients with known hypersensitivity of ropivacaine, history of mental illness, use of psychotopic medicine, pain medication prior to surgery, history of impaired sensation.

Design outcomes

Primary

Measure	Time frame
Requirements of analgesics	—

Secondary

Measure	Time frame
Hemodynamic changes	—

Countries

Japan

Contacts

Public ContactEiji Masaki

Tohoku University Hospital Anesthesiology

ejmasaki@m.tohoku.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026