A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria

A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria - A Crossover trial of Furosemide versus Gosha-Jinki-Gan for Nocturnal Polyuria

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004153

Enrollment

Registered

2010-09-10

Start date

2006-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nocturia due to nocturnal polyuria

Interventions

furosemide, peroral administration, 20mg after lunch, once per day gosha-jinki-gan, peroral administration, 7.5g/day, 3 times/day

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) 2 or more of I-PSS nocturia score 2) 35% or more of nocturnal polyuria index 3) 50 or more of age 4) systolic blood pressure 140mmHg or more, or diastolic blood pressure 90mmHg or more, or under treatment of hypertension 5) 20pg/ml or more and less than 200 pg/ml of serum BNP level

Exclusion criteria

Exclusion criteria: 1) obvious neurogenic bladder 2) severe hypertension 3) severe complications

Design outcomes

Primary

Measure	Time frame
nocturnal urinary frequency and nocturnal polyuria index	—

Secondary

Measure	Time frame
safety, quality of life, serum BNP level, blood pressure, body fluid compartments	—

Countries

Japan

Contacts

Public ContactKoji Yoshimura

Kyoto University Graduate School of Medicine Urology

ky7527@kuhp.kyoto-u.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026