Bronchial asthma Chronic cough
Conditions
Interventions
None listed
Sponsors
Kyoto University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Adult bronchial asthma patients who have chronic airway inflammation, airway contraction, airway hyperrresponsiveness and clinical symptom. Adult chronic cough patients who have cough symptom lasting more than 8 weeks, and have neither abnormal shadow of chest X ray nor wheezing. Adult healthy never smokers. 2)Patients who succeeded in induced sputum test 3)Patients who gave consult to the study
Exclusion criteria
Exclusion criteria: 1)Patients who had upper respiratory infection within previous 8 weeks 2)Patients who treated with systemic corticosteroids within previous 4 weeks 3)Patients who smoked within previous 6 months or had smoked more than 5 pack-years in the past 4)Patients who take inhaled corticosteroids, expectorants, antibiotics, antiallergy agents 5)Patients who have other respiratory diseases 6)Patients who are concidered inappropriate by physicians in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Induced sputum mucin levels | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationships between induced sputum mucin levels and various clinical indices which are listed below 1)Exhaled nitric oxide levels 2)Indices of pulmonaly function 3)Indices of airway responsiveness 4)Indices of capsaicin cough sensitivity 5)Cell differentials and biomarkers of induced sputum 6)Scores of questionnaires | — |
Countries
Japan
Contacts
Public ContactTomoko Tajiri
Kyoto University Graduate School of Medicine Department of Respiratory Medicin
Outcome results
None listed