Binary investigation on the Effects of antiplatelet agents post-PCI: the Necessity of considering vascular Endothelial Function in post coronary Intervention pharmacotherapy

Binary investigation on the Effects of antiplatelet agents post-PCI: the Necessity of considering vascular Endothelial Function in post coronary Intervention pharmacotherapy - BENEFIT

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000004065

Enrollment

Registered

2010-08-18

Start date

2010-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angina pectoris and myocardial infarction

Interventions

Cilostazol group Follow up period:6-9 months Cilostazol Aspirin Ticlopidine or clopidogrel Control group Follow up period:6-9 months Aspirin Ticlopidine or clopidogrel

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who were implanted coronary stent

Exclusion criteria

Exclusion criteria: 1)Patients who are bleeding 2)Congestive heart failure 3)Severe hepatic dysfunction or renal dysfunction or medical history of hypersensitivity to the investigational drugs 4)Pregnant or lactating women, or women who wish to become pregnant 5)Pulse rate at rest >= 80/min 6)Receiving warfarin-potassium therapy

Design outcomes

Primary

Measure	Time frame
FMD(Flow-mediated vasodilatation)	—

Secondary

Measure	Time frame
Target Lesion Revascularization Target Vessel Revascularization MACCE(major adverse cardiac-cerebral event)	—

Countries

Japan

Contacts

Public ContactHiroyoshi Mori

Showa University Fujigaoka Hospital Department of Cardiology

hymori@med.showa-u.ac.jp045-971-1151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026