Normal Healthy volunteer
Conditions
Interventions
None listed
Sponsors
A Society for Impedance study
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: No gastrointestinal symptom. No endoscopic findings in the upper gastrointestinal tract. Normal healthy subjects.
Exclusion criteria
Exclusion criteria: Hiatal hernia of more than 2 cm in length. Organic disease in upper gastrointestinal tract diagnosed by endoscopy. (Cases more than 1 year after Hp eradication can be included to this study) Patients with medication of PPI, H2-blocker, Ca antagonist, prokinetics and drug which affect gastrointestinal motility. History of previous gastrointestinal or thoracic surgery. Patients with severe heart disease, blood disease, renal disease, liver disease or malignancy. Pregnant woman or woman with possibility of pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median value, 25% value and 75% value of number of reflux events of each physical type an of each acidity in the distal esophagus (5 cm above the lower esophageal sphincter (LES)) Mean and SE of %time pH < 4 in the distal esophagus | — |
Secondary
| Measure | Time frame |
|---|---|
| Median value, 25% value and 75% value of number of reflux events of each physical type an of each acidity in the proximal esophagus (15 cm above the lower esophageal sphincter (LES)) Median value, 25% value and 75% value of number of superimposed reflux events in the distal esophagus | — |
Countries
Japan
Contacts
Public ContactOsamu Kaawamura
Gunma University Hospital Department of Gastroenterology
Outcome results
None listed