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Brain magnetic resonance spectroscopic study among cancer patients with chemotherapy

Brain magnetic resonance spectroscopic study among cancer patients with chemotherapy - Brain magnetic resonance spectroscopic study among cancer patients with chemotherapy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000004013
Enrollment
80
Registered
2010-08-06
Start date
2010-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

None listed

Sponsors

Reserch Center for Innovative Oncology National Cancer Center Hospital East
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with pathological diagnosis of breast cancer 2.Patients who are informed of their diagnosis 3.Patients with Performance status of 0-1 4.Patients was with full written consent 5.Patients who will undergo surgical operation 6.Patients will or will not be treated by adjuvant chemotherapy (doxorubicin and cyclophosphamide followed by a taxan)

Exclusion criteria

Exclusion criteria: 1.Patients who is not able to understand this study because of dementia, delirium, or other cognitive disorder 2.Patients who is not able to understand this study because of major depression, schizophrenia, bipolar disorder or other psychiatric disorder 3.Patients for whom MRI is contraindicated 4.Patients with epilepsy, meningitis and neural degnerative disorder 5.Patients with brain metastasis 6.Patients with recurrent breast cancer 7.Patients with bilateral breast cancer 8.Patients with past history of any other cancer 9.Patients who have undergone chemotherapy before this study 10.Patients with serious somatic disease 11.Patients who are judged to be inappropriate for this study by their physician in charge

Design outcomes

Primary

MeasureTime frame
Changes in density of GABA in brain

Secondary

MeasureTime frame
Changes in density of another amino acid in brain

Countries

Japan

Contacts

Public ContactAsao Ogawa

Reserch Center for Innovative Oncology National Cancer Center Hospital East Psycho-Oncology Division

asogawa@east.ncc.go.jp04-7134-7013

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026