breast cancer
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with pathological diagnosis of breast cancer 2.Patients who are informed of their diagnosis 3.Patients with Performance status of 0-1 4.Patients was with full written consent 5.Patients who will undergo surgical operation 6.Patients will or will not be treated by adjuvant chemotherapy (doxorubicin and cyclophosphamide followed by a taxan)
Exclusion criteria
Exclusion criteria: 1.Patients who is not able to understand this study because of dementia, delirium, or other cognitive disorder 2.Patients who is not able to understand this study because of major depression, schizophrenia, bipolar disorder or other psychiatric disorder 3.Patients for whom MRI is contraindicated 4.Patients with epilepsy, meningitis and neural degnerative disorder 5.Patients with brain metastasis 6.Patients with recurrent breast cancer 7.Patients with bilateral breast cancer 8.Patients with past history of any other cancer 9.Patients who have undergone chemotherapy before this study 10.Patients with serious somatic disease 11.Patients who are judged to be inappropriate for this study by their physician in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in density of GABA in brain | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in density of another amino acid in brain | — |
Countries
Japan
Contacts
Reserch Center for Innovative Oncology National Cancer Center Hospital East Psycho-Oncology Division