Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Tokai University School of Medicine, Department of Internal Medicine, Division of Gastroenterology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with histologically or clinically diagnosed HCC 2. Patients with HCC that reveals contrast-enhancement in the arterial phase of dynamic CT scan 3. Patients who do not have indication of surgical resection or local therapy including radiofrequency ablation and percutaneous ethanol injection 4. Patients who have not received previous treatment for HCC, or patients who were treated for HCC more than 3 months ago and do not reveal recurrence in the treated lesions. 5. Patients who do not have invasion to bile ducts, extrahepatic metastasis, or tumor thrombus in the portal or hepatic veins. 6. Patients with Child-Pugh class A or B. 7. Serum bilirubin level < 3 mg/dl 8. Serum creatinine level < 1.5 mg/dl 9. White blood cell count >= 3000/mm3 10. Platelet count >= 50000/mm3 11. Hemoglobin concentration >= 9.5 g/dl 12. Patients with PS score (ECOG) of 2 or less.
Exclusion criteria
Exclusion criteria: 1. Patients who have hypersensitiby to iodine or contrast media. 2. Patients who have severe thyroid or heart diseases. 3. Patients who have uncontrolled malignancies other than HCC. 4. Patients who are pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to progression | — |
Countries
Japan
Outcome results
None listed