Patients undergoing diagnostic bronchoscopy
Conditions
Interventions
At the start Male<
=65y.o. female<
=70 y.o. midazolam 0.075mg/kg Male>
65y.o. female>
70 y.o. midazolam 0.05mg/kg subsequent dose: half of the first dose q20min.
Sponsors
Nagoya University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who are going to undergo diagnostic bronchoscopy at the Nagoya University Hospital. 2) Patients aged 20 years or older 3) Patients able to fill out a questionnaire 4) Written informed consent from the patients 5) Adequate organ function, as follows: AST/ALT <= 100 IU/L T. Bil <= 1.5 mg/dL Scr <= 1.5 mg/dL SpO2 >= 90% or PaO2 >= 60 torr (room air )
Exclusion criteria
Exclusion criteria: Patients with at least one of the following conditions are ineligible. 1) Patients with type II respiratory failure who take or need home oxygen therapy 2) Patients with obstructive sleep apnea syndrome who need positive airway pressure ventilation 3) History of myocardial infarction within 6 weeks 4) Having mental disorders unable to mutual understanding 5) History of grave drug allergic reaction or allergic reaction to midazolam 6) Acute angle-closure glaucoma 7) Neuromuscular disease (such as myasthenia gravis) 8) Patients who are taking 9) Pregnancy, breast feeding and suspected pregnancy 10) Inadequate for bronchoscopy 11) Patients whose participation in the trial is judged to be inappropriate by the attendeing doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient's discomfort during bronchoscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety and memory during bronchoscopy, willingness to accept a repeat bronchoscopy, complications of the procedure, vital sign during bronchoscopy, time of bronchoscopy, dose of lidocaine, diagnostic rate | — |
Countries
Japan
Contacts
Public ContactKazuyoshi Imaizumi
Nagoya University Graduate School of Medicine Department of Respiratory Medicine
Outcome results
None listed