Coronary artery disease with dyslipidemia
Conditions
Interventions
strong statin alone
strong statin plus EPA 1800mg daily
Sponsors
Kurashiki central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Post-PCI patients with chronic coronary artery disease or acute coronary syndrome patients having >= 75% coronary artery stenosis according to the ACC/AHA classification 2) Patients with hypercholesterolemia taking strong statin or those meeting one of the dyslipidemia criteria: LDL-C >= 100mg/dl. TG >= 150mg/dl, HDL-C < 40mg/dl 3) Age: 20<=, < 75 years 4) Patients who can be followed up for longer than 18 months after PCI 5) Patients who have given written informed consent
Exclusion criteria
Exclusion criteria: 1) Patients who have hypersensitivity to EPA 2) Patients who had cerebral accident in the past 6 months 3) Pregnant women and women suspected of being pregnant 4) Patients with gastrointestinal ulcer in active phase 5) Patients with bleeding 6) Patients who have very poor choleresis or severe liver dysfunction 7) Patients who are ineligible for this study 8) Patients with severe renal dysfunction or undergoing dialysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In non-PCI lesions with >= 50% stenosis according to the AHA classification, 1) change in MLD during the follow-up period 2) coronary revascularization | — |
Secondary
| Measure | Time frame |
|---|---|
| MACCE: death, nonfatal myocardial infarction, cerebral accident, unstable angina requiring hospitalization | — |
Countries
Japan
Contacts
Public ContactYasushi Fuku
Kurashiki central Hospital Department of Cardiology
Outcome results
None listed