A randomized study in oral immunotherapy for food allergy by Ministry of Health, Labour and Welfare in JAPAN

A randomized study in oral immunotherapy for food allergy by Ministry of Health, Labour and Welfare in JAPAN - A randomized study in oral immunotherapy (OIT) for food allergy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003943

Enrollment

Registered

2010-07-23

Start date

2010-07-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

food allergy

Interventions

rush oral immunotherapy allergen avoidance diet

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) children (ages 5-15 years). 2) patients with immediate allergic reactions to egg or milk. 3) egg: the threshold dose inducing allergic reactions <= 4 g. milk: the threshold dose inducing allergic reactions <= 10 ml. 4) available to verbal communication and hospitalization.

Exclusion criteria

Exclusion criteria: 1) patients who have been treated with rush oral immunotherapy. 2) patients with poorly controlled asthma or atopic dermatitis.

Design outcomes

Primary

Measure	Time frame
A comparison of the dose response to double-blind, placebo-controlled food challenge (DBPCFC) before and after therapy between rush OIT group and elimination group. We will define the thresholds for clinically significant reactions in DBPCFC.	—

Countries

Japan

Contacts

Public ContactNaoka Itoh

The University of Tokyo Department of Pediatrics

naoka_i@hotmail.com03-3815-5411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026