Evaluation of the required concentration of dexmedetomidine after abdominal aorta aneurysm surgery with fentanyl- or remifentanil-based anesthetic management

Evaluation of the required concentration of dexmedetomidine after abdominal aorta aneurysm surgery with fentanyl- or remifentanil-based anesthetic management - Evaluation of the required plasma concentration of dexmedetomidine after abdominal aorta aneurysm surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003901

Enrollment

Registered

2010-07-14

Start date

2007-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aorta aneurysm

Interventions

Fentanyl is used for analgesia during surgery Remifentanil is used for analgesia during surgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient undergoing abdominal aorta aneurysm surgery with an age of 20 years or more.

Exclusion criteria

Exclusion criteria: Exclusion criteria were severe cardiovascular disease and concurrent systemic disorders. Patients with arrhythmias such as atrial fibrillation or disturbance in the conduction system and those receiving alpha-methyldopa or clonidine treatment were also excluded from this study.

Design outcomes

Primary

Measure	Time frame
Plasma concentration of dexmedetomidine and outcome	—

Secondary

Measure	Time frame
Hemodynamics, respiratory condition, sedative condition	—

Countries

Japan

Contacts

Public ContactTakayuki Kunisawa

Asahikawa Medical College Anesthesiology and Critical Care Medicine

0166-68-2583

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026