nongonococcal urethritis (Chlamydia trachomatis urethritis, Mycoplasma genitalium urethritis)
Conditions
Interventions
levofloxacin 500mg once daily p.o. 7days
Sponsors
Department of Infectious Diseases and Infection Control, Jikei University School of Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1)age: more than 20 years old 2)sex: male 3)outpatient or hospitalization: both are included 4)patient with suspicious symptoms of nongonococcal urethritis 5)patient detected C. trachomatis or M. genitalium by bacteriological examination
Exclusion criteria
Exclusion criteria: 1)patient detected N.gonorrhoeae by microscopic examination or bacteriological examination etc. 2)patient who has been administered other antibiotics and his symptom has been improved before starting administration of the study drug 3)patient administered fluoroquinolone within a week before starting administration of the study drug 4)patient with severe infection desease, who cannot be expected efficacy of oral administration therapy 5)patient with severe underlying disease or complications, who cannot be evaluated efficacy and safety of the study drug 6)patient with a history of fluoroquinolone allergies 7)patient with severe cardiac or hepatic dysfunction 8)patient with moderate renal dysfunction (Criteria: Serum Creatinine >= 2mg/dL) 9)patient with convulsive disorders like epilepsy or with a history of these deseases 10)patient disqualified as target by doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bacteriological efficacy two weeks after the end of treatment by levoflixacin | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical efficacy two weeks after the end of treatment by levofloxacin | — |
Countries
Japan
Outcome results
None listed