Intralesional steroid injections for esophageal strictures after endoscopic submucosal dissection for esophageal squamous cell neoplasms: A phaseII trial

Intralesional steroid injections for esophageal strictures after endoscopic submucosal dissection for esophageal squamous cell neoplasms: A phaseII trial - A phaseII trial of steroid injection for post ESD esophageal stricture

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003894

Enrollment

Registered

2010-07-12

Start date

2010-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal squamous cell neoplasms

Interventions

Intralesional steroid injections for esophageal strictures after endoscopic submucosal dissection for esophageal squamous cell neoplasms

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) histologically confirmed esophageal squamous cell neoplasms 2)invaion depth is estimated within submucosa 3)Circumferece of tumor extension is more than 3/4 of lumen 4)without lymphnode metastasis 5)without organ failure 6)obtained written informed consent

Exclusion criteria

Exclusion criteria: 1)undergoing anticoagulant therapy 2)intraoperative perforation during ESD 3)inappropriate for this trial

Design outcomes

Primary

Measure	Time frame
incidence of esophageal strictures	—

Secondary

Measure	Time frame
frequency of balloon dilations, frequency of adverse events	—

Countries

Japan

Contacts

Public ContactHanaoka Noboru

Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Gastrointestinal Oncology

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026