Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Kyoto Prefectural University of Medicine, Division of Gastroenterology and Hepatology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The following HCC patients who are curatively treated with RFA. 1. not less than 20, less than 80 years of age. 2. Performance status of the patients are 0-2. 3. Child-Pugh class A or B. 4. Bone marrow function and hepatic/renal functions are well maintained. a White blood cell count more than 2000/mm3, less than 10000/mm3. b. Platelet count more than 50000/mm3. c. AST and ALT less than 150IU/L d. T. Bil less than 3.0mg/dl. e. Cr less than 1.5mg/dl 5. All patients gave written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patient who has uncontrollable severe infectional disease. 2. Patient who has allergic disease or autoimmune disease requiring treatment. 3. Patient who is associated with malignant hypertension, severe congestive heart disease, unsatble angina, myocardial infarction within 6 months prio to registration, severe pulmonary fibrosis and active interstitial pneumonia. 4. Patient who cannot undergo enhanced CT scan or MRI due to some reason such as allergy for contrast media or renal dysfunction. 5. Patient who has uncontrollable associated cancer. 6.Patient with severe drug allergy. 7.Patient with severe psychiatric disorder. 8.In pregnancy or lactation. 9. Patient with HIV or HTLV-1 infection. 10.Patient who is inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Three-year recurrence-free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival, disease-specific survival, immunological response, safety | — |
Countries
Japan
Contacts
Public ContactTakeshi Ishikawa
Kyoto Prefectural University of Medicine Division of Gastroenterology and Hepatology
Outcome results
None listed