Efficacy and safety of long-term use of topical corticosteroids following corneal transplantation

Efficacy and safety of long-term use of topical corticosteroids following corneal transplantation - Long-term use of topical steroids following corneal transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003829

Enrollment

Registered

2010-07-01

Start date

2010-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Following penetrating keratoplasty

Interventions

use of topical low-dose corticosteroids (0.1% fluoromethorone) three times a day discontinuation of topical corticosteroids

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Eyes that had penetrating keratoplasty for more than 1 years ago, and the grafts remain clear with the use of topical corticosteroids

Exclusion criteria

Exclusion criteria: active ocular infection eyes that need topical corticosteroids for uveitis or ocular allergy

Design outcomes

Primary

Measure	Time frame
Development of immunological rejection during the study period	—

Secondary

Measure	Time frame
Development of local complications associated with the use of topical corticosteroids	—

Countries

Japan

Contacts

Public ContactJun Shimazaki

Tokyo Dental College, Ichikawa General Hospital Ophthalmology

jun@eyebank.or.jp0473-22-0151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026