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The comparative study between direct renin inhibitor and angiotensin II receptor antagonist in hypertensive patients with chronic kidney disease

The comparative study between direct renin inhibitor and angiotensin II receptor antagonist in hypertensive patients with chronic kidney disease - The comparative study between direct renin inhibitor and angiotensin II receptor antagonist

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000003817
Enrollment
40
Registered
2010-07-01
Start date
2010-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic kidney disease

Interventions

Aliskiren fumarate Valsartan

Sponsors

Division of Nephrology, Hypertension and Endocrinology, Itabashi Hospital, Nihon University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Outpatients with chronic kidney disease at stage 1-4 2) Patients prescribed angiotensin II receptor antagonist over one year 3) Patients prescribed angiotensin II receptor antagonist at most high dose 4) Patients with 150/90 mmHg or less of home blood pressure

Exclusion criteria

Exclusion criteria: 1) Patients with a serious liver damage 2) Patients with a serious renal damage 3) Patients with serum potassium concentration over 5.5 mEq/L

Design outcomes

Primary

MeasureTime frame
Blood pressure, Urinary albumin excretion

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026