Clinical study on the effects of various single nucleotide polymorphisms on the analgesic and adverse effects of opioids

Clinical study on the effects of various single nucleotide polymorphisms on the analgesic and adverse effects of opioids - Genomic polymorphisms and effects of opioids

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003814

Enrollment

300

Registered

2010-06-23

Start date

2010-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intraoperative and postoperative pain in patients undergoing colectomy

Interventions

evaluation of analgesic effects of fentanyl using electricity-induced pain test

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing laparoscopic colectomy

Exclusion criteria

Exclusion criteria: patients with serious co-existing disease, patients taking tranquilizers or analgesics

Design outcomes

Primary

Measure	Time frame
analgesic effects of fentanyl eveluated by pain test, amount of remifentanil required intraoperatively, amount of fentanyl required posoperatively, postoperative pain scale, adverse effects of fentanyl, genome-wide analysis of genomic polymorphisms	—

Countries

Japan

Contacts

Public ContactHayashida, Masakazu

Saitama Medical University International Medical Center Department of Anesthesiology

hayashi4@saitama-med.ac.jp042-984-4394

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026