Comparison of intraocular pressure lowering effects among four prostaglandin analogues: parallel administration to the bilateral eyes of normal subjects.

Comparison of intraocular pressure lowering effects among four prostaglandin analogues: parallel administration to the bilateral eyes of normal subjects. - Comparison of intraocular pressure lowering effects among four prostaglandin analogues: parallel administration to the bilateral eyes of normal subjects.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003810

Enrollment

Registered

2010-06-24

Start date

2010-06-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma, ocular hypertension

Interventions

The subjects instilled the latanoprost in the one eye and the taravoprost was instilled in the contralateral eye once a day at 9:00 p.m. for 2 weeks. The subject visited the hospital on Day 0,7 and 14

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 20 years or older healthy volunteers with 18 mmHg or lower intraocular pressure in both eyes prior to the study.

Exclusion criteria

Exclusion criteria: subjects with glaucoma or ocular hypertension (including secondary and exfoliative glaucoma diagnosed before), keratitis and conjunctivitis,a 2mmHg or greater laterality in the mean intraocular pressure, and using contact lenses. Subjects taking drugs which influence the intraocular pressure and having a history of drug allergy to the prostaglandin analogues.

Design outcomes

Primary

Measure	Time frame
intraocular pressure lowering effects	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026