autoimmune pancreatitis
Conditions
Interventions
None listed
Sponsors
Department of Gastroenterology, University of Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who meet asian diagnostic criteria of autoimmune pancreatitis 2) Patients who have received steroid maintenance therapy(<7.5mg prednisolone/day) for more than three years 3) Patients whose abdominal and chest CT performed within 6months show no active extrapancreatic lesions related to autoimmune pancreatitis. 4) Patients whose IgG is below 1600 mg/dl at least for one year 5) Patients whose serum amylase and lipase are not abnormally high. Patiens whose amylase is high, but p-amylase is not high are allowed to join this research. 6) Patients whose KL-6 is normal. 7) Patients whose TSH is below 10 uIU/ml. 8) Patients who are 20 years old or older. 9) Patients who give written informed consent after receiving enough explanation about the present research.
Exclusion criteria
Exclusion criteria: 1) Patients who need steroid therapy for other diseases than autoimmune pancreatitis 2)Patients with past history of hospitalization due to relapse during maintenance steroid therapy 3) Patients whom doctors in charge judged that the entry is inadequate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of no relapse, clinical relapse, and serological relapse in three years after tapering steroid | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphological change of pancreas Pancreatic endocrine function Occurrence of malignancy Survival time | — |
Countries
Japan
Outcome results
None listed