Chemically assisted ESD in the esophagus and the colon

Chemically assisted ESD in the esophagus and the colon - CA-ESD in the esophagus and the colon

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003787

Enrollment

Registered

2010-06-21

Start date

2010-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early stage esophageal cancer, esophageal dysplasia, early stage colonic cancer, and colonic adenoma with an indication of ESD

Interventions

Using mesna as a submucosal injection solution.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Superficial lesions in the esophagus and the colon with indication of ESD removal.

Exclusion criteria

Exclusion criteria: History of hypersensitivity to mesna and women who were pregnant, lactating, or hoping to become pregnant during this study period

Design outcomes

Primary

Measure	Time frame
Procedural success rate	—

Secondary

Measure	Time frame
En bloc resection rate Complication and side effect rate The healing process of post-therapeutic ulcerations Histological analysis of sampled specimens	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026