A comparative study of the therapeutic efficacy of azithromycin and tosufloxacin against pediatric respiratory infection with Mycoplasma pneumoniae possessed macrolide-resistant gene.

A comparative study of the therapeutic efficacy of azithromycin and tosufloxacin against pediatric respiratory infection with Mycoplasma pneumoniae possessed macrolide-resistant gene. - Kawasaki Pediatric 1(KP1)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003771

Enrollment

250

Registered

2010-06-17

Start date

2012-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mycoplasma infection

Interventions

Treatment with azithromycin Treatment with tosufloxacin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pediatric patients was suspected of Mycoplasma infection

Exclusion criteria

Exclusion criteria: side effect and allergic reaction No consent Refusal of taken a medicine Patient with progressive or severe disease Severe renal and hepatic dysfunction Patient with allergic history to azithromycin or tosufloxacin Patient judged of inappropriate by doctor

Design outcomes

Primary

Measure	Time frame
The clinical response of azithromycin and tosufloxacin treatment. Decline of fever within 48hrs duration of fever Total fever period Chest X-ray finding WBC, CRP	—

Secondary

Measure	Time frame
Bacteriological therapeutic efficacy response The change of the mycoplsmaPCR amount of nasopharynx after antibiotic administration	—

Countries

Japan

Contacts

Public ContactTakaaki Tanaka

Kawasaki medical college Department of Pediatrics

takaaki51@hotmail.com0864621111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026