Effect of local steroid injection or application on the epithelial regeneration promoting action of postoperative artificial ulcer following endoscopic submucosal dissection in early-stage esophageal cancer - Preventing esophageal stenosis due to scar formation during the epithelial regeneration process

Effect of local steroid injection or application on the epithelial regeneration promoting action of postoperative artificial ulcer following endoscopic submucosal dissection in early-stage esophageal cancer - Preventing esophageal stenosis due to scar formation during the epithelial regeneration process - Kenacort injection or application for the esophagus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003762

Enrollment

Registered

2010-06-15

Start date

2009-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early esophageal cancer

Interventions

In the local steroid injection group, 0.2 ml (2 mg) TA was locally injected into the ulcer floor at 8 mm intervals with extra care to avoid injection and following 5 min balloon dilatation (12-15 mm i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with early-stage esophageal cancer who had undergone endoscopic submucosal dissection with an excision of three fourths to the full circumference of the esophagus from whom informed consent was obtained

Exclusion criteria

Exclusion criteria: nothing in particular

Design outcomes

Primary

Measure	Time frame
The primary outcome measure was the difference in stricture rate between groups determined by gastrografin esophagograms on PODs 5, 8, 12, 15, 20, 30, and 60 between 2 gouups.	—

Secondary

Measure	Time frame
The number of EBD procedures, the number of procedure-related bleeding events	—

Countries

Japan

Contacts

Public ContactShintaro Fujhara

Kagawa University Department of gastroenterology

joshin@med.kagawa-u.ac.jp087-891-2156

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026