Colorectal neoplasm
Conditions
Interventions
Magnifying observation using magnifying endoscope.
Sponsors
Osaka Medical Center for Cancer and Cardiovascular Diseases
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are undergoing colonoscopy for positive fecal occult blood test, surveillance colonoscopy after endoscopic resection, and colonoscopic resection of colorectal neoplasms.
Exclusion criteria
Exclusion criteria: 1)Patients who had previously undergone histological examination. 2)Patients with open bleeding or symptoms suspected colonic stenosis. 3)Patients with inflammatory bowel disease, familial polyposis and known colon neoplasm. 4)Patients who are receiving anticoaglant medication or having bleeding tendency. 5)Patients with severe organ failure. 6)Patients without informed consent. 7)Patients who are regarded in-eligible by the doctor who participates in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity of NBI-ME in accurate decision for low grade dysplasia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Procedure time (insertion and observation), Diagnostic ability (sensitivity, specificity and accuracy) for high grade dysplasia, low grade dysplasia and non-neoplastic lesion using NBI-nonME and NBI-ME, Accurate clinical decision rate (resect and discard, resect and send and leave it in situ) using NBI-nonME and NBI-ME. Diagnostic accuracy according to the lesion size (<5mm, >6mm). Adverse events. | — |
Countries
Japan
Contacts
Public ContactYoji Takeuchi
Osaka Medical Center for Cancer and Cardiovascular Diseases Gastrointestinal Oncology
Outcome results
None listed