Elderly patients with previously untreated non-squamous non-small cell lung cancer
Conditions
Sponsors
Lung Cancer Experts Network
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytologically proven non-squamous non-small cell lung cancer 2)70 years or older 3)Previously untreated stage III/IV patients (no indication of surgery or radiotherapy) 4)ECOG PS 0-2 5)With measurable lesion 6)Adequate organ function 7)Life expectancy more than 2 months 8)Eligible in case of controlled pleural effusion 9)Eligible in case of controlled brain metastases 10)Written informed consent
Exclusion criteria
Exclusion criteria: 1)Interstitial pneumonia or pulmonary fibrosis detectable on chest X-ray 2)Patients with superior vena cava syndrome 3)History of uncontrollable diabetes mellitus, active angina pectoris, recent myocardial infaction, and recent brain infarction 4)History of active infection 5)History of severe psychological disease 6)Hystory of active double cancer 7)History of severe drug allergy 8)History of severe heart disease 9)Patients with immunotherapy or vaccine therapy 10)Patients whose participation in the trial is judged to be inappropriate by the attending doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival Overall survival 1 year survival rate Safety QOL | — |
Countries
Japan
Contacts
Public ContactNobuhiko Seki
Teikyo University Hospital Division of Medical Oncology
Outcome results
None listed