Impact of functional imaging on the evaluation of treatment effect after neoadjuvant chemoradiation therapy for non-small cell lung cancer

Impact of functional imaging on the evaluation of treatment effect after neoadjuvant chemoradiation therapy for non-small cell lung cancer - Impact of functional imaging on the evaluation of treatment effect after neoadjuvant chemoradiation therapy for non-small cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003675

Enrollment

Registered

2010-05-31

Start date

2010-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small Cell Lung Cancer

Interventions

Undergo PET/CT and plain MRI (including diffusion-weighted image) before and after neoadjuvant chemoradiation therapy.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Histologically confirmed Non-small cell lung cancer. 2.Adequate bone marrow function WBC more than 4000/ul, Platelet count more than 100,000/ul. 3.Adequate liver function. (T.Bil less than 1.5mg/dl) 4.Adequate renal level. (serum creatinin less than 1.5mg/dl, Creatinine clearlance more than 60mg/dl) 5.Adequate pulmonary function (PaO2 more than 70Torr) 6. No other severe complications. Agreement for the protocol by physicians, surgeons and radiologists is essential. 7.Written informed consent to participate in the trial is necessary

Exclusion criteria

Exclusion criteria: 1.Malignant pleuritis or malignant pericarditis. 2.Pleural dissemination. 3.Patients with severe complications. a.Pulmonary fibrosis. b.Severe heart disease.(Uncontrollable angina or myocardial infarction within the past 3 months) c.Uncontrollable Diabetes Mellitus. d.Severe infectious disease e.Other unsuitable patient judged by a physician. 4.Women during pregnancy or lactating.

Design outcomes

Primary

Measure	Time frame
Accuracy of treatment effect prediction by functional imaging	—

Secondary

Measure	Time frame
Pathological response of preoperative therapy	—

Countries

Japan

Contacts

Public ContactYoichi Otomi

University of Tokushima Department of radiology

otomi.yoichi@tokushima-u.ac.jp088-633-9283

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026