Clinical research for hemoperfusion therapy with an immobilized polymyxin B (PMX) fiber column in patients with severe influenza pneumonia in Vietnam and Japan

Clinical research for hemoperfusion therapy with an immobilized polymyxin B (PMX) fiber column in patients with severe influenza pneumonia in Vietnam and Japan - Clinical research for hemoperfusion therapy in patients with severe influenza pneumonia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003669

Enrollment

Registered

2010-05-27

Start date

2008-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe influenza pneumonia

Interventions

Blood purification therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Infection with influenza A virus is suspected. The definitive diagnosis is made when the specimens obtained from the patient are A positive by Polymerase Chain Reaction (PCR) method or rapid test kit. (2) The patient with moderate or severe pneumonia. 1) New infiltration lesion detected on the first CXR or newly occurred among the film series. 2) The patient who fulfills PaO2/FiO2 ratio of 80-300. (3) The patient whose symptom onset is no later than 7 days. (4) The patient from whom (or whose deputy) a written consent is obtained.

Exclusion criteria

Exclusion criteria: (1) Individuals who do not meet the above mentioned criteria for cases. (2) Individuals who do not agree to sign the informed consents. (3) Individuals with Immune deficiency. (4) Individuals who are decided to be NOT suitable for this research by a clinical doctor.

Design outcomes

Primary

Measure	Time frame
survival	—

Secondary

Measure	Time frame
serial changes in blood test, levels of inflammatory mediators, physical findings and radiolgical images	—

Countries

Japan,Asia(except Japan)

Contacts

Public ContactJin Takasaki

National Center for Globsl Health and Medicine Disease Control and Prevention Center/Departmant of Respiratory Medicine

jin@dcc.go.jp0332027181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026