A randomized control trial for preventing decline of cognitive functions in the community living elderly with mild cognitive impairment

A randomized control trial for preventing decline of cognitive functions in the community living elderly with mild cognitive impairment - A randomized control trial for preventing decline of cognitive functions in the elderly with MCI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003662

Enrollment

100

Registered

2010-06-01

Start date

2010-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment

Interventions

Intervention group: Supervised aerobic exercise for 1 year Control group: Lecture about disease and health (3 times per year)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Living in Obu city 2) CDR 0.5 3) give a written informed consent to the participation in the present study

Exclusion criteria

Exclusion criteria: 1) Having serious or unstable illnesses 2) history of psychiatric disease 3) Receiving of anti-Alzheimer drugs

Design outcomes

Primary

Measure	Time frame
Cognitive function: ADAS Brain volumetry: MRI Brain function: FDG PET and fNIRS	—

Secondary

Measure	Time frame
Cognitive functions: Mini-mental state examination, Clinical dementia rating, Wechsler memory scale-R, Digit span, Stroop test, SDMT, Word fluency, Trail making test, Geriatric depression scale, Clock drawing, VBTA, Ray-Osterrieth complex figure test, Raven's Colored Progressive Matrices, Key search test, A part of standard language test of aphasia Physical functions: muscle strength, gait performance Activity: Tokyo Metropolitan Institute of Gerontology Index, Life-space assessment	—

Measure

Time frame

Cognitive functions: Mini-mental state examination, Clinical dementia rating, Wechsler memory scale-R, Digit span, Stroop test, SDMT, Word fluency, Trail making test, Geriatric depression scale, Clock drawing, VBTA, Ray-Osterrieth complex figure test, Raven's Colored Progressive Matrices, Key search test, A part of standard language test of aphasia Physical functions: muscle strength, gait performance Activity: Tokyo Metropolitan Institute of Gerontology Index, Life-space assessment

—

Countries

Japan

Contacts

Public ContactShimada Hiroyuki

National Center for Geriatrics and Gerontology Section for Health Promotion

shimada@ncgg.or.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026