The clinical effect of Cyclooxygenase (COX)-2 selective inhibitors on pollakisuria and lumbar- abdominal pain in patients with prostate cancer who undergo interstitial seed implantation - Randomized control trial-

The clinical effect of Cyclooxygenase (COX)-2 selective inhibitors on pollakisuria and lumbar- abdominal pain in patients with prostate cancer who undergo interstitial seed implantation - Randomized control trial- - The clinical effect of Cox-2 inhibitor on symptoms in patients who undergo prostate brachytherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003649

Enrollment

150

Registered

2010-05-21

Start date

2010-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostate cancer

Interventions

alpha-1 blocker alpha-1 blocker + COX-2 inhibitor

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: newly diagnosed localized prostate cancer patients

Exclusion criteria

Exclusion criteria: Patients with severe cardiac disease, severe liver dysfunction and severe renal dysfunction

Design outcomes

Primary

Measure	Time frame
Improvement of rate in IPSS, QOL-index, OABSS and QOL questionnaire (SF8 and EPIC) during 3 months after seed implantation	—

Countries

Japan

Contacts

Public ContactNobumichi Tanaka

Nara Medical University Department of Urology

sendo@naramed-u.ac.jp0744-22-3051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026