Malignant colorectal obstruction
Conditions
Interventions
Stent placement in the region of colonic stenosis.
Other treatments except surgical intervention.
Sponsors
Japan Interventional Radiology in Oncology Study Group (JIVROSG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inoperable, symptomatic obstruction in rectum or sigmoid cancer. 2. No clinical obstruction in oral side GI tract. 3. Difficulty in surgical colostomy or no refusal by the patient. 4. Palliative prognosis index less than 6. 5. Written informed consent from the patients. 6. Twice measurement of symptom score and health-related quality-of-life.
Exclusion criteria
Exclusion criteria: 1. Indication for surgical colostomy. 2. Possibility of definitive surgery for colorectal obstruction. 3. Bleeding from the treatment area requiring hemostatic treatments. 4. More than 4 weeks after the beginning of the symptom from colorectal obstruction. 5. Clinically significant cardiac failure, renal failure, or bleeding tendency. 6. Difficulties in the evaluation of quality-of-life. 7. Pregnancy. 8. Contraindication decided by participating physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the symptoms from colorectal obstruction. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of health-related QOL, toxicity profile, and survival time. | — |
Countries
Japan
Contacts
Public ContactYasuaki Arai
National Cancer Center Hospital Division of Diagnostic Radiology
Outcome results
None listed