Malignant bone tumor
Conditions
Interventions
Percutaneous bone plasty (PBP)
Medical therapy
Sponsors
Japan Interventional Radiology in Oncology Study Group (JIVROSG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Painful bone metastases or primary bone tumors in thoracic spine, lumbar spine, or pelvic bones 2. No existing treatment for pain relief other than PBP or medical therapy 3. Palliative prognosis index less than 6. 4. Written informed consent from the patients 5. Twice measurement of health-related quality-of-life and RDQ
Exclusion criteria
Exclusion criteria: 1. Cardiac failure requiring medical therapy 2. Extensive bone destruction in posterior aspect of vertebral bodies or compression of spinal cord by the tumor 4. Bone destruction in acetabulum 5. Uncontrollable bleeding tendency 6. History of advanced drug allergy 7. Active infectious disease 8. Active inflammatory process in intended bone 9. Under radiotherapy for the bone tumor or less than 4 weeks after the completion of RTx without progression of the symptom 10. Indication for strontium-89 radiotherapy 11. Difficulty of keeping treatment position for one hour with medical or physical treatments 12. Incapable in dose escalation of analgesics 13. Pregnancy 14. Contraindication decided by attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of back pain | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of health-related QOL/improvement of Roland-Morris Disability Questionnaire: RDQ/ toxicity profile/ survival time. | — |
Countries
Japan
Contacts
Public ContactYasuaki Arai
National Cancer Center Hospital Department of Diagnostic Radiology
Outcome results
None listed