Intensive lipid and blood pressure lowering and cardiovascular outcome: Randomised controlled trial on patients with coronary artery disease and type 2 diabetes

Intensive lipid and blood pressure lowering and cardiovascular outcome: Randomised controlled trial on patients with coronary artery disease and type 2 diabetes - Randomised controlled trial of intensive lipid and blood pressure lowering in diabetic CAD patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003548

Enrollment

1000

Registered

2010-04-28

Start date

2010-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease and type 2 diabetes

Interventions

Intensive therapy that targeted systolic blood pressures of less than 120 mm Hg and LDL cholesterol of 70-85 mg/dl. Any treatment strategies that are currently available in clinical practice can be u

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Type 2 diabetic patients with coronary artery disease and history of myocardial infarction whose systolic blood pressure is >130 mmHg (more than two occasions) and LDL cholesterol is >100mg/dl.

Exclusion criteria

Exclusion criteria: (1) With active malignant tumor (2) On hemodialysis due to chronic renal failure (3) Contraindication of statin therapy (4) Acute myocardial infarction, stroke and unstable angina (as acute coronary syndrome)within 3 months (5) pregnancy and breast feeding (6)Any factors likely to limit adherence to interventions

Design outcomes

Primary

Measure	Time frame
Composite endpoint: total mortality, myocardial infarction, stroke, unstable angina	—

Secondary

Measure	Time frame
Total and cardiovascular mortality, myocardial infarction, stroke, unstable angina,new onset of heart failure, hospital administration due to heart failure,end stage renal disease	—

Countries

Japan

Contacts

Public ContactShinichiro Ueda

University of the Ryukyus Graduate School of Medicine Department of Clinical Pharmacology & Therapeutics

suedano9@dream.com0988951195

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026