Phase 3 study of relationship between peripheral venous reservation and lymphedema of upper limbs in patients with breast cancer who received axillary lymphnode dissection

Phase 3 study of relationship between peripheral venous reservation and lymphedema of upper limbs in patients with breast cancer who received axillary lymphnode dissection - Phase 3 study of relationship between peripheral venous reservation and lymphedema of upper limbs in patients received axillary lymphnode dissection

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003497

Enrollment

Registered

2010-04-17

Start date

2009-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Interventions

Patients receive peripheral venous reservation on the non-postoperative arm with adjuvant chemotherapy, Doxorubicin 50-60mg/square meter,or Epirubicin 60-100mg/square meter followed Docetaxel 60-75mg

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Unilateral breast cancer 2) Patients who received axillary lymphnode dissection level I or more. 3) Sufficient organ function 4) No incidence of lymphedema of upper limbs (including doctor's clinical determination ) 5) Written informed consent 6) Suitable for receiving adjuvant chemotherapy including Anthracycline followed Docetaxel for four couses.

Exclusion criteria

Exclusion criteria: 1) Bilateral breast cancer. 2) Severe disease (hepatic, renal, heart or endocrine ) 3) Eastern Cooperative Oncology Group performance status (PS) of 2 to 4. 4) No lymphedema of upper limbs subjectively or objectively. 5) Allergic reaction to Anthracycline or/and Docetaxel.6) Other conditions inadequate for this research

Design outcomes

Primary

Measure	Time frame
Incidence of lymphedema of upper limbs	—

Secondary

Measure	Time frame
Incidence and grade of phlebitis. Difficulty of peripheral venous reservation	—

Countries

Japan

Contacts

Public ContactYasuhiro Yanagita

Gunma Prefectural Cancer Center Department of Breast Oncology

yyanagita@gunma-cc.jp+81-276-38-0771

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026