Malignant refractory ascites
Conditions
Interventions
Peritoneovenous shunting (Denver peritoneovenous shunting or transjugular-transhepatic peritoneovenous shunting)
Any treatments except peritoneovenous shunting
Sponsors
Japan Interventional Radiology in Oncology Study Group (JIVROSG)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Refractory ascites caused by malignant diseaser 2. Symptomatic ascites refractory to various therapies except paracentesis 3. Palliative prognosis index less than 6. 4. Written informed consent from the patients. 5. Twice measurement of health-related quality-of-life
Exclusion criteria
Exclusion criteria: 1. Non-malignant ascites 2. Previous peritoneovenous shunt 3. More than four weeks after the occurrence of refractory ascites 4. Bloody, mucinous or infectious ascites 5. Malignant peritoneal methothelioma 6. Ascites caused by liver cirrhosis 7. Clinically significant cardiac failure, renal failure, or bleeding tendency 8. Difficulties in the evaluation of quality-of-life 9. Pregnancy 10. Contraindication decided by attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the symptoms from ascites. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of health-related QOL/ toxicity profile/ survival time. | — |
Countries
Japan
Contacts
Public ContactMiyuki Sone
National Cancer Center Hospital Department of Diagnostic Radiology
Outcome results
None listed