Hypertensive patients receiving combined therapy with candesartan cilexetil and diuretic
Conditions
Interventions
combination tablets (ARB/diuretics) ARB/diuretics combinations
Sponsors
Kanazawa Medical University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patient who was diagnosed as hypertension 2.Patient who recieves continuous candesartan and diuretic treatment 3.ambulatory patient 4.Patient who understands the contents of the informed consent form. 5.Patient who agrees with contraception during the study period
Exclusion criteria
Exclusion criteria: 1.Patient who is anuric and/or dialysis 2.Patient with ARF (acute renal failure) 3.Patient with sodium - and potassium - depletion / sodium - and potassium - depleted patients 4.Patient who is pregnant or possibly pregnant 5.Patients with a history of hypersensitivity to ingredients of Ecard HD (candesartan cilexetil-hydrochlorothiazide) or other thiazide or thiazide-like diuretics 6.Patient who is determined to be excluded from the study due to any reason by the study doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Change in blood pressure (absolute value) 2.Changes in uric acid (absolute value) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.TC, TG, HDL-C 2.BNP 3.cystatin C 4.blood glucose level (HbA1c, fasting blood sugar) 5.urinary albumin, urinary sodium 6.safety : serum potassium | — |
Countries
Japan
Contacts
Public ContactKouji Kajinami
Kanazawa Medical University Hospital Department of Cardiology
Outcome results
None listed