Verification of the effectiveness of the combination therapy with an oral antibiotics and Adapalene for the treatment of acne vulgaris.

Verification of the effectiveness of the combination therapy with an oral antibiotics and Adapalene for the treatment of acne vulgaris. - Verification of the effectiveness of the combination therapy with an oral antibiotics and Adapalene for the treatment of acne vulgaris.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003415

Enrollment

150

Registered

2010-03-31

Start date

2010-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acne vulgaris

Interventions

Adapalene gel will be applied to the surface of the face overall once daily after washing the face before retiring in the evening for 4 weeks. In the first 2 weeks, Faropenem Sodium Hydrate will be al

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with acne vulgaris expressing from moderate to severe symptoms in guideline 2) Patients who gave their written informed consent

Exclusion criteria

Exclusion criteria: 1) Patients taking some drugs(oral,topical or injective agents)expected to be indicated for the treatment of acne within 4 weeks 2) Patients with hypersensitivity to any of the study drugs 3) Patients continuously receiving non-steroidal anti-inflammatory drugs 4) Women who are pregnant,might be pregnant or lactating 5) Patients who are considered unsuitable for this study by the investigator

Design outcomes

Primary

Measure	Time frame
Decrease percentage of the number of inflammatory lesion.	—

Secondary

Measure	Time frame
-Change of the number of inflammatory lesion and comedone -Safety -Change in patient QOL(Skindex-16)	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026