Effects of preservation of celiac branch of the vagus nerve after distal gastrectomy for gastric cancer. A prospective randomized controlled phase II study.

Effects of preservation of celiac branch of the vagus nerve after distal gastrectomy for gastric cancer. A prospective randomized controlled phase II study. - Effects of preservation of celiac branch of the vagus nerve after distal gastrectomy for gastric cancer. A prospective randomized controlled phase II study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003364

Enrollment

200

Registered

2010-03-23

Start date

2010-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

distal gastrectomy with preservation of celiac branch of vagus nerve distal gastrectomy without preservation of celiac branch of vagus nerve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.gastric cancer with T1 invasion (lesion confined to the mucosa or the submucosa) and the tumors found to have submucosal invasion after EMR or ESD. 2.require distal gastrectomy 3.resectable lymph-nodes with preservation of hepatic and celiac branch of vagus nerve 4.Age; 20-90 years 5.Performance status 0-1 6.resectable D1 lymph-nodes with curability A or B 7.no abnormity in gallbladder or bile passage 8.informed consent is obtained

Exclusion criteria

Exclusion criteria: 1.post cholecystectomy or with abnormity in bile passage 2.peritoneal dissemination, hepatic metastasis, distant metastasis, invade other organ 3.history of any other malignancy which is including synchronal double cancer, but they are not including the carcinoma in situ or intramucosal cancer diagnosed as cure by local procedure 4.double cancer of disease free for less than 5 years 5.severe respiratory disease 6.cardiac infarction 7.hepatic cirrhosis or active hepatitis 8.chronic renal failure accompanied by hemodialysis 9.diabetes (HbA1c>9.0) 10.patient who is judged as an inappropriate case by the doctor in charge

Design outcomes

Primary

Measure	Time frame
Primary outcome is the rate of gallstone two years after operation.	—

Countries

Japan

Contacts

Public ContactYuichiro Doki

Osaka University, Graduate School of Medicine Gastroenterological Surgery

ydoki@gesurg.med.osaka-u.ac.jp06-6879-3251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026