Preventive effect on recurrence of hepatocellular carcinoma by branched chain amino acids after curative hepatectomy

Preventive effect on recurrence of hepatocellular carcinoma by branched chain amino acids after curative hepatectomy - Prevention of HCC-recurrence by branched chain amino acids after hepatectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003363

Enrollment

140

Registered

2010-03-25

Start date

2010-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatocellular carcinoma

Interventions

Intervention:term 4 years dose Reevact 4g/time frequency 3 times/day Control 1:term 4 years no drug

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with hepatocellular carcinoma who undergo curative hepatectomy at second Department of Surgery, Dokkyo Medical University

Exclusion criteria

Exclusion criteria: 1)recurrence of hepatocellular carcinoma 2)Stage IV 3)Patients who were given branched chain amino acid within 4 weeks of regisration 4)hepatic coma>III 5)serum bilirubin level more than 3.0 mg/dL 6)Congenital abnormality of branched chain amino acids- metabolism

Design outcomes

Primary

Measure	Time frame
disease-free suravival rate	—

Countries

Japan

Contacts

Public ContactTokihiko Sawada

Dokkyo Medical University Second Department of Surgery

tsawada@dokkyomed.ac.jp0282-86-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026