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A multicenter study to investigate characteristics of bacterial wound contamination in clean orthopaedic surgeries

A multicenter study to investigate characteristics of bacterial wound contamination in clean orthopaedic surgeries - Characteristics of bacterial wound contamination in clean orthopaedic surgeries

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000003360
Enrollment
700
Registered
2010-03-19
Start date
2010-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clean Orthopaedic Surgeries

Interventions

None listed

Sponsors

Surgical Site Infection Prevention Project(SSIPP) workgroup meeting
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Consecutive patients undergoing open reduction and internal fixation of closed fractures(ORIF), spinal surgeries, and joint surgeries in 5 hospitals.

Exclusion criteria

Exclusion criteria: 1)patients who had received any anti-microbial agents during the week before surgery, 2)surgery involving the infected site, 3)patients with skin trouble in surgical site, 4)hand surgery, 5)foot surgery, 6)arthroscopic surgery, 7)patients with renal failure (serum creatinine level of more than 1.5 microgram/dl at admission), 8)patients receiving hemodialysis, 9)operation longer than 6 hours, 10)open fracture, 11)nonunion, 12)peripheral nerve surgery, 13)tuberculous spondylitis, 14)antimicrobial prophylaxis other than cefazolin, 15)re-operation, 16)external fixation, 17)percutaneous pinning, 18)patients who are pregnant, 19)patients less than 20 years old, 20)patients with allergy to the beta-lactam antibiotics, 21)patients of iodine hypersensitivity, 22)patients receiving multiple operations in the same day, 23)intraoperative radiotherapy 24)operation with unexpected dirty procedures.

Design outcomes

Primary

MeasureTime frame
Incidence of bacterial wound contamination increases after normal saline irrigation in clean orthopaedic surgeries.

Secondary

MeasureTime frame
(1)Characteristics of the isolated bacteria. (2)Incidence of MRSA contamination. (3)Risk factors of bacterial wound contamination.

Countries

Japan

Contacts

Public ContactIga Toru

Tokyo Metropolitan Tama Medical Center Department of Orthopaedic Surgery

042-323-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026