Efficacy and tolerability of paroxetine in patients with burning mouth syndrome

Efficacy and tolerability of paroxetine in patients with burning mouth syndrome - Efficacy and tolerability of paroxetine in patients with burning mouth syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003266

Enrollment

Registered

2010-03-01

Start date

2010-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burning mouth syndrome

Interventions

A total of 80 subjects,12- week study. Paroxetine hydrochloride is started at a dose of 10 mg once a day at after supper, and the dosage is adjusted every 2 weeks according to the clinical symptoms.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Depressive condition assessing by SDS or PHQ-9. Tongue pain with a minimum duration of 6 months.

Exclusion criteria

Exclusion criteria: Patients with clinically significant renal, hepatic cardiovascular diseases. Subjects taking psychotropic drugs or antidepressant within the past four weeks Abnormal hematologic examination finding Candidiasis. Pregnancy, nursing.

Design outcomes

Primary

Measure	Time frame
The cumulative proportion of responders after 12 weeks of medication. The incidence of adverse reaction during 12 weeks.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026