The evaluation of intestinal permeability for damage of mucosal injury from NSAIDS

The evaluation of intestinal permeability for damage of mucosal injury from NSAIDS - Evaluation of intestinal permeability

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003258

Enrollment

Registered

2010-04-01

Start date

2010-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Volunteer

Interventions

Dicrofenac sodium 25mg 3times/day +Placebo 3times/day +Omeprazole20mg/day for 7days Dicrofenac25mg 3times/day +Rebamipide300mg/day +Omeprazole20mg/day for 7days

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients who have no mucosal injury 2) Patients who have signed the informed consent

Exclusion criteria

Exclusion criteria: 1) Patients who have allergy for study drugs. 2) Patients who got intestinal operation. 3) Patients who suffer from ileus. 4) Patients who fit the pacemaker. 5) Patients who take calcium antagonist, nitrous acid drug, NSAIDS, anti ulcer drug, and alcohol ordinary before 2weeks. 6) Patients who have diabetes. 7) Patients who have renal failure and liver failure. 8) Patients who have heart failure. 9) Patients who have (have been suspected) renal infection. 10) Patients whom doctor judged as inadequate.

Design outcomes

Primary

Measure	Time frame
To evaluate the correlation between various sugars permeability of Stomach, Small intestine and Large intestine and injury by observation of CE	—

Countries

Japan

Contacts

Public ContactMakoto Sasaki

Aichi Medical University Gastroenterology

msasaki@aichi-med-u.ac.jp+81-561-62-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026