Colon cancer
Conditions
Interventions
UFT/LV UFT 300mg/m2/day LV 750mg/day for 28 days followed by a 7-day rest period (one cycle=5 weeks)X5 cycle or TS-1 80mg/m2/day for 28 days followed by a 14-day rest period (one cycle = 6 we
Sponsors
Yamaguchi University Department of Srgery and Clinical Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) histopathologically proven colon cancer 2) pathological stage 2 (high risk),3 3) resection of histological curability A was performed 4) ECOG PS 0-2 5) 20-80 years old 6) no prior chemotherapy and radiotherapy 7) adequate organ function 8) Written informed consent
Exclusion criteria
Exclusion criteria: 1) Contraindications of using UFT, LV, TS-1 2) active double cancer except ca. in situ 3) Severe postoperative complication 4) Serious coexisting illness a)uncontrolled diabetes mellitus b)uncontrolled hypertension c)history of myocardial infarction, unstable angina within 6 months prior to the registration severe d)liver cirrhosis e)pulmonary dysfunction 5) pregnant or nursing patient or with intent to bear baby 6) mental disorder or psychiatric symptom 7) HIV infection 8) Disqualified by attending doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival,Compliance, Relation of risk facter, Measurement of anticancer drug-sensitive facter | — |
Countries
Japan
Contacts
Public ContactTadahiko Enoki
Yamaguchi University Department of Surgery and Clinical Science
Outcome results
None listed