Effectiveness of therapeutic hypothermia for unconscious adult patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest

Effectiveness of therapeutic hypothermia for unconscious adult patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac arrest - Hypothermia first

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000003203

Enrollment

Registered

2010-03-01

Start date

2010-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac arrest

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) aged 18 years and older, (2) a presumed cardiac origin of the arrest according to the Utstein Style reporting guidelines, (3) ROSC by standard CPR or/and ACLS, and (4) persistent coma after ROSC(GCS 3,4,5).

Exclusion criteria

Exclusion criteria: (1) not cardiac origin, (2) tympanic-membrane temperature below 30degree on arrival at the emergency room, (3) cardiogenic shock after ROSC, (4) pregnancy, (5) the Glasgow-Pittsburgh overall performance category of 2 (moderate overall disability), 3 (severe overall disability), or 4 (vegetative state) before cardiac arrest, and (6) their families refused to give informed consent to participate in the study.

Design outcomes

Primary

Measure	Time frame
a favorable neurological outcome at hospital discharge (CPC: Cerebral Performance Categories)	—

Secondary

Measure	Time frame
survival to hospital discharge or death	—

Countries

Japan

Contacts

Public ContactTaketomo Soga

Surugadai Nihon University Hospital Department of emergency medicine

0332931711

Outcome results