Development of non-invasive methods for diagnosis of asthma and chronic obstructive pulmonary disease (COPD) and for difference between asthma and COPD.

Development of non-invasive methods for diagnosis of asthma and chronic obstructive pulmonary disease (COPD) and for difference between asthma and COPD. - Development of non-invasive method for difference between asthma and COPD.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003193

Enrollment

Registered

2010-03-01

Start date

2010-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma and chronic obstructive pulmonary disease (COPD).

Interventions

Inhalation of procaterol hydrochloride 20 microgram.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy never-smokers without any presence and histories of chronic respiratory and allergic diseases, and patients with asthma and chronic obstructive pulmonary disease (COPD) recruited from out-patient clinic of Shinshu University Hospital.

Exclusion criteria

Exclusion criteria: Healthy subjects who have smoking history or have histories of asthma or chronic respiratory diseases are excluded. Asthyma patients who have smoking history or severe cardiovascular diseases are excluded. COPD patients complicated with asthma or who have histories of asthma or severe cardiovascular diseases are excluded.

Design outcomes

Primary

Measure	Time frame
Decreases in respiratory impedance and dynamic hyperinflation and increases in exhaled nitric oxide 30 minute after the inhalation of a short-acting bronchodilator.	—

Secondary

Measure	Time frame
Analysis of proteins and peptides in exhaled breath condensate obtained before the inhalation of a short-acting bronchodilator.	—

Countries

Japan

Contacts

Public ContactKeisaku Fujimoto

Shinshu University School of Medicine Department of Biomedical Laboratory Sciences, Health Sciences.

keisaku@shinshu-u.ac.jp0263-37-2393

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026