Additive effects of short-acting bronchodilators in COPD patients who still had dyspnea in their daily lives despite long-acting bronchodilators.

Additive effects of short-acting bronchodilators in COPD patients who still had dyspnea in their daily lives despite long-acting bronchodilators. - Additive effects of short-acting bronchodilators on dyspnea in COPD.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003192

Enrollment

Registered

2010-03-01

Start date

2010-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease

Interventions

Single inhalation of procaterol hydrochloride 20 microgram. Single inhalation of oxytropium bromide 0.2 mg.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with moderate to severe chronic obstructive pulmonary disease (COPD) in stable phase, who recruited from outpatient clinic of Shinshu University Hospital and still have dyspnea on exertion despite therapy with long-acting bronchodilators including tiotropium at least.

Exclusion criteria

Exclusion criteria: The patients who considered to have risks for exercise test, such as coronary vascular disease, arythmia, and heart failure are excluded from this study.

Design outcomes

Primary

Measure	Time frame
Exercise tolerance and maximum Borg Scale for dyspnea on shuttle walking test.	—

Secondary

Measure	Time frame
Spirometry and dynamic hyperinflation.	—

Countries

Japan

Contacts

Public ContactKeisaku Fujimoto

Shinshu University School of Mdedicine Department of Biomedical Laboratory Sciences, Health Sciences

keisaku@shinshu-u.ac.jp0263-37-2393

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026