Crossover trial of single ingestion of mulberry leaf extract on postprandial hyperglycemia in pre-diabetic subjects

Crossover trial of single ingestion of mulberry leaf extract on postprandial hyperglycemia in pre-diabetic subjects - Crossover trial of single ingestion of mulberry leaf extract on postprandial hyperglycemia in pre-diabetic subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000003154

Enrollment

Registered

2010-03-01

Start date

2006-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

Carbohydrate-rich meal intake after ingestion of placebo

blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate-rich meal intake after ingestion of mulberry leaf extract (low-dose)

blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate-rich meal intake after ingestion of mulberry leaf extract (middle-dose)

blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate-rich meal intake after ingestion of mulberry leaf extract (high-dose)

blood collection before and 30, 60, 90 and 120 min after the meal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Fasting plasma glucose in the range of 100-140 mg/dl

Exclusion criteria

Exclusion criteria: pregnancy, lactation, severe medical illnesses, and the concurrent use of any agent for the control of blood glucose

Design outcomes

Primary

Measure	Time frame
Postprandial plasma glucose and serum insulin levels	—

Countries

Japan

Contacts

Public ContactToshiyuki Kimura

National Agricultural Research Center for Tohoku Region Biomass Research Team (Tohoku Region)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026