impaired glucose tolerance
Conditions
Interventions
During the initial six months, four group session were conducted and an individual session is conducted biannually by public health nurses or dieticians.
The control group received only general verbal
Sponsors
Natiional Hospital Organization Kyoto Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects with impired glucose tolerance (IGT), aged 30-60 years, were recruited through helath checkups conducted at 32 collaborative center. The recruitment started in March 1999 and was completed in December 2002. A two-step strategy was adopted for indentifying subjects with IGT. The criteria were: 1) fasting plasma glucose >=5.6mmol/l but <7.0 mmol/l, 2) casual plasma glucose (CPG) >=7.8mmol/l but <11.1mmol/l when blood was drawn within 2 hours after a meal, or CPG >=6.1mmol/l but 7.8mmol/l when blood was drawn 2 hours or more after meal, or 3) a diagnosis of IGT based on a previous 75 g oral glucose test. Then, IGT were diagnosed based on the World Health Organization's criteria.
Exclusion criteria
Exclusion criteria: 1) a preveous diagnosis of diabetes mellitus other than gestational diabetes 2) a history of gastrectomy 3) physical conditions such as ischemic heart disease, heart failure, exercise-induced asthma and orhopedic problems where exercise was not allowed by a doctor, 4) deinitive liver and kidney diseases 5) autoimmune diseases 6) a hibit of heavy alcohol drinking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative incidence of diabetes mellitus | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of body weight, BMI, waist cicumference, blood glucose, insulin, HbA1c, blood pressure, lipids, liver function, and health behavior | — |
Countries
Japan
Contacts
Public ContactNaoki Sakane
Natiional Hospital Organization Kyoto Medical Center Clinical Research Institute
Outcome results
None listed